Professor (2012/11-) & Vice Dean (2017/08-), College of Medicine, China Medical University (CMU)
Director, Mind-Body Interface Research Centre, China Medical University Hospital (2006/08-)
Chief, Department of General Psychiatry, China Medical University Hospital (2002/3-)
Honorary Professor of Institute of Psychiatry-King's College London (2008/11-)
Professional Experience
2014/08-2017/08, Chairman, Graduate Institute of Neural and Cognitive Sciences, China Medical University (CMU)
1999/5-2002/3, Attending physician, Department of Psychiatry, Wan Fang Medical Centre & Taipei Medical University Hospital
Education & Training
1988-1995, M.D., Kaohsiung Medical College, Kaohsiung, Taiwan
1995-1999, Chief Resident and Resident, Taipei City Psychiatric Centre
2005-2008, PhD, Institute of Psychiatry, King’s College London, UK
Awards
2016, The International Society for the Study of Fatty Acids and Lipids (ISSFAL): Early Career Award
2013, Psychopharmacology Award from the British Association for Psychopharmacology (UK)
2013, GlaxoSmithKline Depression and Anxiety Research Award, Taiwanese Society of Psychiatry, Taiwan
2013, Professor Wen-Ho Chang Research Award, Taiwanese Society of Biological Psychiatry and Neuropsychopharmacology, Taiwan
2012, Pacific Rim College of Psychiatrists: Young Psychiatrists Award
2012 and 2014, The International Society for the Study of Fatty Acids and Lipids (ISSFAL): New Investigator Award
2012, Teaching Excellency Award, China Medical University Hospital
2012, Psychiatric Research Society Annual Meeting Travel Award (USA)
2011, Thomson Reuters Research Front Award
2011, GlaxoSmithKline Depression and Anxiety Research Award, Taiwanese Society of Psychiatry, Taiwan
2011, Initiative Research Cooperation among Top Universities between UK and Taiwan, National Science Council, Taiwan
2011, Scientific Physician, China Medical University Hospital (CMUH)
2010, Ta-You Wu Memorial Award, National Science Council, Taiwan
2010, the Elite Physician of the Year, CMUH
2009 and 2004, the Best Physician of the Year, CMUH
2008, Professor Wen-Ho Chang Research Award, Taiwanese Society of Biological Psychiatry and Neuropsychopharmacology, Taiwan
2008, Professor Robert Kerwin International Award from the British Association for Psychopharmacology (UK)
2008-2010, National Alliance for Research on Schizophrenia and Depression (NARSAD) Young Investigator Award (USA)
2007-2008, China Medical University Elite Faculty Scholarships
2007, Travel Award of the 20th ECNP
2006-2007, China Medical University Hospital Elite Scholarships
2006, Professor Janssen’s Schizophrenia Research Award, Society of Psychiatry, Taiwan; Guided Tour Poster Nomination of the 19th European College Neuropsychopharmacology (ECNP); Travel Awards from King’s College London; Travel Awards from Taipei Representative Office in the U.K.
2005-2006, Elite Program of Taiwan Merit Scholarships (TMS), Ministry of Education, Taiwan
Research Grants
Biological mechanisms and clinical subtyping for comorbidity of chronic pain and depression: The molecular approach of central sensitization. (2017-2020, MOST106-2314-B-039-027-MY3)
N-3 fatty acids as the first-line antidepressant therapy: From biomarkers to clinical subtypes (2016-2018, 3-Year Innovative Research Grant (IRG) of Integrated Research Grants in Health and Medical Sciences from National Health Research Institutes NHRI-EX105-10528NI)
Pharmacogenomic approach to inflammation theory of depression: Genome-wide associations of interferon-α-induced depression (2015-2017, 2 Years, MOST104-2314-B-039-022-MY2)
Subtyping in depression with inflammation and pain: The mechanisms underlying major depressive disorder with painful symptoms (2015-2016, China Medical University, CMU104-S-16-03)
Effects of a melatonin receptor agonist on clinical manifestations and peripheral biological markers of circadian rhythm (2015-2016, China Medical University, CMU104-S-44)
Pharmacogenomics of n-3 polyunsaturated fatty acids treatment for major depressive disorder: Genome-wide associations. (2014-2017, Ministry of Science and Technology MOST 103-2320-B-039-039- MY3)
Major depression and omega-3 fatty acids: From cellular mechanisms to clinical implications (2014-2016, NSC-NCBR [National Centre for Research and Development, Poland] Joint Research Projects. NSC 102-2923-B-039 -002 -MY3)
Omega-3 fatty acid on preventing depression in pregnant women (2013-2015, NSC-RS [Royal Society] Joint Research Projects 102-2911-I-039-501)
Phospholipid hypothesis of depression: From molecular biology, neuroimaging to behaviour (2012-2015, Project for Excellent Junior Research Investigators NSC101-2628-B-039-001-MY3)
The antidepressant effects for omega-3 fatty acids in cellular inflammation mechanisms (2014-2015, China Medical University CMU103-S-03)
Neuropsychobiology of Brain Theta-burst Stimulation: A Mind-body Interface for Depression (2012-2014, Innovative Research Grant (IRG) of Integrated Research Grants in Health and Medical Sciences from National Health Research Institutes NHRI-EX101-10144NI)
The protective effect of astrocyte condition medium for glutamate-induced excitotoxicity in cortical neuron (2013-2014, China Medical University Hospital DMR-103-078)
Genetic markers for interferon-alpha-induced depression in patients with chronic hepatitis C viral infection (2012-2013, China Medical University Hospital DMR-102-068)
Heterogeneity of depression: The role of genetic variations in subtyping major depressive disorder (2011-2012, China Medical University Hospital DMR-101-081)
Neurocognitive and neurobiological mechanisms of interferon-induced depression (2009-2012, Integrated Research Project NSC 98-2627-B-039-003)
N-3 polyunsaturated fatty acids in the prevention and treatment for IFN-induced depression (2009-2012, NSC 98-2628-B-039-020-MY3)
The biological mechanism of n-3 polyunsaturated fatty acids in depression. Initiative Research Cooperation among Top Universities between UK and Taiwan (2010-2011, NSC 99-2911-I-039-002)
The biological mechanism of somatic symptoms in depression: The role of polyunsaturated fatty acids. National Alliance for Research on Schizophrenia and Depression (NARSAD) Young Investigator Award 2008-2010
Polyunsaturated fatty acids as biomarkers in classifying subtypes of depression (2008-2010, National Science and Technology Program for Biotechnology and Pharmaceuticals (NSTPBP) Translational Medicine Project, 97(2)-TRA-001)
Peripheral gene expression of PLA2 and COX2 in IFN-alpha-induced depression (China Medical University Hospital 2009-2010, DMR99-114)
The role of neurocognitive and neurobiological markers in interferon-induced depression: an exploratory study (China Medical University 2009-2010, CMU97-336)
The role of polyunsaturated fatty acids on sickness behaviour and depression induced by interferon therapy in patients with hepatitis C viral infection (2006-2009, NSC 95-2320-B-039-037-MY3)
Proteomic analysis in interferon-induced sickness behavior and depression in patients with hepatitis C viral infection (CMU95-143)
The effect of fish oil in bipolar disorder: a double-blind placebo-controlled trail for the antidepressant and maintenance effects of in bipolar disorder (2006-2008, DOH 95F022)
Effect of fish oil diet on rat’s forced-swimming test (2005-2006, NSC 94-2314-B-039-027)
The effect of fish oil in major depressive disorder: a double-blind placebo-controlled monotherapy trail to demonstrate the therapeutic and preventive effects of depression (2005-2008, DOH 94F044)
Omega-3 polyunsaturated fatty acids in women with major depressive disorders during pregnancy and afterbirth: from the perspectives of epidemiology, membrane psychopathophysiology, dietary differences and the double-blind placebo-controlled therapeutic trail (2002-2005, NSC 91-2320-B-039-017, 92-2320-B-039-003, 93-2320-B-039-001)
Omega 3 fatty acids in schizophrenic disorder: from the perspectives of the double-blind placebo-controlled therapeutic trail, membrane psychopathophysiology, and dietary differences (2001-2004, NSC 90-2320-B-038-046, 91-2320-B-039-010, 92-2320-B-039-002)
Omega 3 fatty acids in major depressive disorder: the composition of Omega 3 PUFAs in red cell membrane & parallel-group, double blind, placebo-controlled therapeutic trail (2000, NSC 89-2320-B-038-046)
Omega 3 fatty acids in major depressive disorder: parallel-group, double blind, placebo-controlled trail (1999, Taipei Medical College, TMC88-Y05-A121)
Lipid, glucose and leptin abnormalities induced by novel antipsychotic drugs (2003-2004, China Medical University Hospital, DMR-92-017)
Effect of omega-3 fatty acid diet on rat’s depressive-like behaviors in forced-swimming test (2004-2005, China Medical University, CMU93-M-24)
Effect of omega-3 fatty acid diet on rat’s reserpine-induced depressive-like behaviours (2005-2006, China Medical University, CMU94-105)
Committee & Membership
Member of Board of Directors, the International Society for the Study of Fatty Acids and Lipids (ISSFAL) (2016-2020)
President of Taiwan Society for Nutritional Psychiatry Research (TSNPR) (since 2016)
Editorial board member of Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) (since 2016)
Council Board Member of the Taiwanese Society of Biological Psychiatry and Neuropsychopharmacology (TSBPN) (since 2015)
President and Committee Chairman, the 1st-6th Mind-Body Interface International Symposium (Since 2010, Supported by the MOST grants)
Vice President, the 6th International Conference on Nutrition and Physical Activity (NAPA 2015)
Editorial board member of Clinical Psychopharmacology and Neuroscience (since 2014)
Council Board Member of the International Society for Nutritional Psychiatry Research (ISNPR) (since 2012)
Honorary Editor of the Journal of Traditional and Complementary Medicine (since 2013)
Editorial board member of the Psychiatry Investigation (since 2012)
International Affair Committee of the Taiwanese Society of Suicidality (since 2010)
Executive editor of the Taiwanese Journal of Psychiatry (since 2009)
Asia Consortium member of the International Society For Pharmacoeconomics and Outcomes Research (ISPOR) (since 2009)
Membership of British Association for Psychopharmacology (2007-2010)
Membership of European College of Neuropsychopharmacology (2007-10)
Membership of International Society for Bipolar Disorders (2005-2010)
Editorial Board of the Bipolar Disorders Update (2006-2008)
Member of Organizing Committee, DEPRESSION: BRAIN CAUSES, BODY CONSEQUENCES, Royal Society of Medicine, Institute of Psychiatry, King’s College London, UK (2007/4/2-3)
Taiwanese Psychiatric Association (#000585)
Taipei Medical Association (#16258)
The Higher Civil Service Examination Certification (#026430)
Selected Publication
Senthil Kumaran S, Shih YH, Chien YC, Huang SY, Gałecki P, Kasper S, Chang JPC, Su KP*. Anti-oxidative effects of melatonin receptor agonist and omega-3 polyunsaturated fatty acids in neuronal SH-SY5Y cells: Deciphering synergic effects on antidepressant mechanisms. Molecular Neurobiology (In Press). (IF 6.19; 25/259 NEUROSCI)
Lin PY, Chang CH, Chongc MFF, Chen H, Su KP*. Polyunsaturated fatty acids in perinatal depression: A systematic review and meta-analysis. Biological Psychiatry 2018 Feb; 43(3): 534-545. (IF 11.4; 6/142 PSY)
Chang JPC, Su KP, Mondelli V, Pariante C. Omega-3 Polyunsaturated Fatty Acids in Youths with Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review and Meta-analysis of Clinical Trials and Biological Studies. Neuropsychopharmacology (Accepted) doi: 10.1038/npp.2017.160. [Epub ahead of print] (IF 6.4; 12/142 PSY)
Borsini A, Alboni S, Horowitz MA, Tojoa LM, Cannazza G, Su KP, Pariante CM, Zunszain PA. Rescue of IL-1β−induced reduction of human neurogenesis by omega-3 fatty acids and antidepressants. Brain, Behavior, and Immunity (Accepted). (IF 6.0; 24/150 IMMUNE)
Gałecka E, Talarowska M, Maes M, Su KP, Górski P, Kumor-Kisielewska A, Szemraj J. Expression levels of interferon-ɣ and type 2 deiodinase in patients diagnosed with recurrent depressive disorders Pharmacological Reports (Accepted).
Su KP*, Yang HT, Chang JP, Shih YH, Guu TW, Kumaran SS, Gałecki P, Walczewska A, Pariante CM. Eicosapentaenoic and docosahexaenoic acids have different effects on peripheral phospholipase A2 gene expressions in acute depressed patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry (Accepted)
Chang JPC, Guu TW, Chen YC, Gałecki P, Walczewska A, Su KP. BanI polymorphism of cytosolic phospholipase A2 gene and somatic symptoms in medication-free acute depressed patients. Prostaglandins Leukotrienes and Essential Fatty Acids (In Press)
Chang JPC, Lai HC, Walczewska A, Pariante CM, Su KP*. Polyunsaturated fatty acids levels and initial presentation of somatic symptoms induced by interferon-alpha therapy in patients with chronic hepatitis C viral infection. Nutritional Neuroscience 2017; 20 (5), 291-296.
Chang HC, Huang KC, Chiu WC, Huang KC, Tang CH, Su KP*. Changes in employment status in bipolar disorder: a longitudinal study with national claims data. Journal of Clinical Psychiatry 2016 Apr; 77(4): e429-35. (IF 5.3; 12/139 PSY SSCI)
Song C,... Kalueff A, Gaikwad S, Su KP. The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer’s disease. Progress Lipid Research 2016;62:41-54. (IF 10.6; 1/81 NUTRITION)
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