Research Professor in Neuroimmunology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Estonia;
Adjunct Professor, Neuroscience Center, University of Helsinki, Finland
Professional Experience
Project leader & Academy of Finland Research Fellow, Neuroscience Center, University of Helsinki, Finland
Education & Training
2001, Ph.D. (Distinction), Faculty of Bioscience, University of Helsinki, Finland
1993, Bachelor of Medicine, Department of Clinical Medicine, Collage of Medicine, Beijing Medical University (now Peking University Health Science Center), China
Awards
2014, The Chinese Scholarship Council honor for supervisor of the best overseas PhD thesis, Finland
2014, The 10th Beijing municipal “HaiJv Overseas Talent Recruitment Program” award, Beijing, China (北京市海聚人才短期项目奖)
2001, Alfthan Prize (Finnish Chemistry Society), Finland
2001, Award for the best academic dissertation of the year, University of Helsinki Viikki Biocenter, Finland
Research Grants
2018 – 2022 Estonian Research Council Top Scientist Mobilitas Plus Grant 2017 (No. MOBTT77): €900,000
2017 – 2019 Beijing Municipal Science and Technology Commission (北京市科委首都临床特色研究重点项目No. Z171100001017021): Capital Clinical Characteristic Research key project on developing a multi-dimensional diagnostic tool for bipolar disorder, RMB ¥1,000,000
2014 – 2016 Academy of Finland: research grant (No. 273108) and National Natural Science Foundation China (No. 81461130016) joint funding for systemic evaluation of cognitive plasticity of schizophrenic patients after music therapy €276,838 + RMB ¥1,000,000
2011 – 2016 Academy of Finland: research fellow grant for work on neuroimmune crosstalk in CNS diseases: (No. 283085) €161,774, (No. 251340) €391,000, (No. 256107) €305,141
2013 – 2018 European Union 7th FP_Health: multinational consortia research grant (No. 602919) for glial opioid receptor interface in analgesia €100,000 (gloria.helsinki.fi)
Committee & Membership
2018 – present, Editorial Board member of Frontiers in Molecular Neuroscience
2017 – present, Scientific Advisory Board member of the Chinese Association of Science & Technology in Finland, (CASTF, www.castf.org)
2015, Co-guest editor for the special issue of the journal Progress in Neuro-Psychopharmacology & Biological Psychiatry
2014, Invited reviewer for ERA_NET NEURON7 call on neuroinflammatory diseases
Selected Publication
Piirainen S., Youssef A., Song C., Kalueff AV., Landreth G., Malm T., and Tian L.* (2017) Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer’s disease: the emerging role of microglia? Neurosci. & Biobehav. Rev. 77:148-164. IF: 8.30
Li ZL., Khan MM., Kuja-Panula J., Guo DY., Chen ZJ., Lahesmaa R., Rauvala H., and Tian L.* (2017) AMIGO2 is involved in T cell functions and its deficiency in mice ameliorates experimental autoimmune encephalomyelitis. Brain Behav. Immun. 62:110-123. IF: 5.96
Li ZL.,Wei H., Piirainen S., Chen ZY., Kalso E., Pertovaara A., and Tian L.* (2016) Spinal versus brain microglial and macrophage activation traits determine the differential neuroinflammatory responses and analgesic effect of minocycline in chronic neuropathic pain. Brain Behav. Immun. 58: 107-117. IF: 5.87
Xiu MH.#, Tian L. #*, Chen S., Tan YL., Chen DC., Chen J., Yang FD., Licinio J., Kosten TR., Soares JC., and Zhang XY.* (2016) Contribution of IL-10 and its -592 A/C polymorphism to cognitive functions in first-episode drug-naive schizophrenia. Brain Behav. Immun. 57: 116-24. IF: 5.87
Okuneva O., Körber I., Li Z., Tian L., Joensuu T., Kopra O., and Lehesjoki AE. (2015) Abnormal microglial activation in the Cstb-/- mouse, a model for progressive myoclonus epilepsy, EPM1. Glia63(3): 400-11. IF: 6.03
Li ZL., Ma L., Kulesskaya N., Voikar V., and Tian L.* (2014) Microglia are polarized to M1 type in high anxiety inbred mice in response to lipopolysaccharide challenge. Brain Behav. Immun. 38: 237-48. IF: 5.89
Ning L., Tian L., Smirnov S., Vihinen H., Llano O., Vick K., Davis RL., Rivera C., and Gahmberg CG. (2013) Interactions between ICAM-5 and 1 integrins regulate neuronal synapse formation. J. Cell Sci. 126: 77-89. IF: 5.33
Tian L.,* Ma L., Kaarela T., and Li ZL. (2012) Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases. [Review] J. Neuroinflamm. 9: 155-159. IF: 4.35
Tian L.,* Rauvala H., and Gahmberg CG. (2009) Regulation of CNS immune responses by neurons. [Review] Trends Immunol. 30 (2): 91-9. IF: 9.90
Tian L.,* Lappalainen J., Autero M., Häninen S., Rauvala H., and Gahmberg CG. (2008) Shedded neuronal ICAM-5 suppresses T cell activation. Blood 111(7): 3615-25. IF: 10.45
